Renue By Science has published a white paper on its Renue Blue Moisturizing Body Cream, reporting that 95% of participants in a four-week consumer perception study said their skin felt smoother. The study was run with Citruslabs and tracked how women perceived changes in dryness, rough texture, fine lines and crepey skin on the body.

The formula is built around a liposomal complex of NAD+ and two of its precursors, NMN and NR, plus Methylene Blue. Liposomal encapsulation, the company says, is designed to carry those ingredients deeper into the skin for better absorption, and Methylene Blue sits alongside CoQ10 and green tea extract in the formula's antioxidant package. Peptides and botanical extracts round out the ingredient list.

The gap it is aiming at

The premise is the most defensible part of the announcement. Anti-aging research has concentrated on the face, and products made for aging skin on the arms, legs and hands have been studied far less, even though Renue By Science says dry, crepey and less-firm body skin is one of the most common concerns raised by women over 30.

"Body skin has been largely overlooked in skin aging research, even though concerns like crepey skin on the arms and legs come up constantly with the women we hear from," said Rebecca Crews, Ph.D., the company's Research Director. She said most participants noticed their skin felt more hydrated within a few days and that reported results kept improving across the four weeks.

What the study actually was

Forty women aged 30 to 65, each with at least one self-reported visible sign of body skin aging, applied the cream once daily for four weeks. Thirty-eight completed it.

That is the whole sample. The 95% figure is the company's own, drawn from its own commissioned study, and it should be read that way rather than as a clinical result.

Limitations

Renue By Science states them plainly, which is more than most supplement white papers manage: this was a virtual, single-arm consumer perception study, and the results reflect what participants said they perceived. There was no control group and no instrument-measured endpoint, so nothing here separates the formula from moisturizing once a day for a month.

Bottom line

A company-run perception study in 38 women is a starting point, not evidence that liposomal NAD+ or Methylene Blue did the work. The company says it continues to invest in human research across its portfolio, and a controlled comparison is the obvious next thing to ask for.